May 13, 2022

Location, Location, Location: Delivering Your IO Asset Directly to the Lymph Node with Amphiphile

Location, Location, Location: Delivering Your IO Asset Directly to the Lymph Node with Amphiphile
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In pharmacology, getting your drug to where it’s needed is everything. In immunology, to elicit an immune response that location is often the lymph node, and the point of delivery are antigen presenting cells. Amphiphile, from Elicio, can make that happen. Whether the cargo is DNA, a peptide, or a small molecule, once linked to the Amphiphile moiety, the construct is taken up by the lymphatic system. First asset in the clinic? A multiple antigen therapeutic for mKRAS.